La Mesa Vacations from $268

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Your La Mesa Vacation

Lock in a La Mesa vacation package that includes everything you need and nothing you don't. Good for gift and craft shops, dining and nightlife, think about staying in the neighborhood of Downtown San Diego. The Magnolia, Santee Lakes and Grossmont College are just a few of the attractions you'll want to explore during your trip to La Mesa. Browse Expedia's wide range of travel options and start organizing your perfect vacation to La Mesa today.

The Latest La Mesa vacation packages

Price found within the past 48 hours. Click for updated prices.
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Save 100% on your flight
Price was $559, price is now $268 per person
$268
per person
Jan 12 - Jan 16
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.4/10 Very Good! (1,619 reviews)
Excellent downtown location. Convenient to The convention center, little Italy and many restaurants.

Reviewed on Oct 13, 2025

Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

4 out of 5
Downtown San Diego
Save 100% on your flight
Price was $768, price is now $394 per person
$394
per person
Dec 31 - Jan 4
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9/10 Wonderful! (1,082 reviews)
The pool area was nice. We did not like the view from our room, especially since it was mentioned before our arrival that we were in San Diego for our wedding. The counterspace in the bathrooms in non-existent. The gift shop, especially for being a Margaritaville, was really disappointing. Everything else was excellent though! We would definitely stay there again.

Reviewed on Oct 17, 2025

Hyatt Vacation Club at The Welk, San Diego Area

Hyatt Vacation Club at The Welk, San Diego Area

3.5 out of 5
Lawrence Welk Resort Village
Save 100% on your flight
Price was $546, price is now $286 per person
$286
per person
Dec 31 - Jan 4
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.2/10 Very Good! (1,483 reviews)
Enjoyed our time. Best pla

Reviewed on Oct 19, 2025

InterContinental San Diego by IHG

InterContinental San Diego by IHG

4 out of 5
Downtown San Diego
Save 100% on your flight
Price was $604, price is now $327 per person
$327
per person
Dec 31 - Jan 4
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.2/10 Wonderful! (1,056 reviews)
I loved how there was a starbucks and so many walkable restaurants in the area. I will say parking was very limited since we do have a tall truck but the staff was super understanding and flexible. Absolutely would return.

Reviewed on Oct 18, 2025

Kona Kai San Diego

Kona Kai San Diego

4 out of 5
Point Loma
Save 100% on your flight
Price was $1,028, price is now $564 per person
$564
per person
Dec 27 - Jan 1
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.4/10 Very Good! (1,010 reviews)
Clean & updated , very pricey for what it is. Basically a hotel room with pool access in a nice area. Not with the price in my opinion. We had a good deal we thought but after the additional cost of parking and resort fees we won’t be back.

Reviewed on Oct 13, 2025

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Discover the most popular places to visit in La Mesa

Mount Helix Park

Learn about the local history of Casa de Oro-Mount Helix when you spend time at Mount Helix Park. Amble around this family-friendly area's waterfront or attend a sporting event.

Mount Helix Park

Computer Museum of America

You can spend an afternoon studying the exhibits at Computer Museum of America during your trip to La Mesa. Attend a sporting event while in this walkable area or simply enjoy the top-notch restaurants.

Computer Museum of America

What to do in La Mesa

San Diego Old Town Trolley Hop-On Hop-Off Tour

San Diego Old Town Trolley Hop-On Hop-Off Tour

$55
per adult
94% of travellers recommend
San Diego Old Town Trolley Hop-On Hop-Off Tour
San Diego: Museum of Illusions Entry Ticket

San Diego: Museum of Illusions Entry Ticket

$35
per adult
San Diego: Museum of Illusions Entry Ticket
Go City: San Diego Explorer Pass - Choose 2 to 7 Attractions

San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway

$124
per adult
86% of travellers recommend
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway
See all activities in La Mesa

La Mesa Hotel Deals

Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

3 out of 5
3888 Greenwood St, San Diego, CA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $150 total per night from Oct 26 to Oct 27
$150 total
Oct 26 - Oct 27
Total with taxes and fees
9/10 Wonderful! (168 reviews)
"Beautiful facility. Quiet. Good breakfast"

Reviewed on Oct 17, 2025

Hampton Inn & Suites by Hilton San Diego SeaWorld
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
$286 nightly
The price is $332 total per night from Oct 29 to Oct 30
$332 total
Oct 29 - Oct 30
Total with taxes and fees
9/10 Wonderful! (2,855 reviews)
"We had a studio suite on the 38th floor and the view was amazing. It was a nice, spacious room, but the bathroom was so tiny and the bed was not very comfortable. The bellman mentioned that there are upgrades planned in the near future though..."

Reviewed on Oct 17, 2025

Manchester Grand Hyatt San Diego
Comfort Inn San Diego Airport At The Harbor

Comfort Inn San Diego Airport At The Harbor

3.5 out of 5
San Diego
$78 nightly
The price is $88 total per night from Nov 11 to Nov 12
$88 total
Nov 11 - Nov 12
Total with taxes and fees
7.8/10 Good! (1,074 reviews)
"I’ve not had breakfast yet,, checked in at 2, it’s now 8:55 pm"

Reviewed on Oct 18, 2025

Comfort Inn San Diego Airport At The Harbor
See all 8,247 properties in La Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

La Mesa Essential Information

Language
English
Currency
U.S dollars
Closest Airport
San Diego Intl. Airport (SAN)
Population
60,100
Max Temp Winter
65ºF
Max Temp Summer
80ºF
Top Sights
San Diego Zoo, Coronado Beach and Old Town San Diego State Park

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Frequently asked questions

How much does a La Mesa vacation package cost?
Offering great value package deals from $268 on Expedia, you'll be pleasantly surprised at how much a vacation to La Mesa costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to La Mesa?
January, October and December are the best times to search for cheap La Mesa vacation packages. Opting to travel in quieter months means you can typically find lower prices on flights and hotels.
How many days is enough for La Mesa?
Usually, a handful of days is enough to visit the major attractions during your La Mesa vacation. However, if you prefer to have some time to chill out or go on day trips, think about extending your trip.
Is it worth booking a vacation package to La Mesa?
It's no wonder a La Mesa vacation is on the to-do list of many travelers. Well-known attractions like Mount Helix Park are just the beginning of things to keep you busy here.
How to find the best La Mesa package deals?
Use Expedia's filters to help you find some fabulous La Mesa package deals. When you start your search, just set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your adventure for midweek, or look for La Mesa package deals in the low season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's usually best to book your vacation package well in advance.
Is it cheaper to book a La Mesa vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your flight, hotel and car rental into one great-value price and enjoy significant savings. You'll usually score a better deal than booking each component individually. And you'll still get the freedom to create a personalized La Mesa vacation by choosing your favorite type of stay, airline and car class.
When to book a vacation package to La Mesa?
Secure fantastic discounts by reserving your flights in advance with Expedia. If being spontaneous is more your style, take advantage of our last-minute deals for an impromptu La Mesa adventure.
How to plan a trip to La Mesa?

  1. Pick your travel dates: What you plan to do in La Mesa and your favorite season will help you decide when to get away.
  2. Set your budget: Factor in expenses like food, flights and transportation when calculating how much to set aside for your trip to La Mesa. Then, choose a property that matches your budget, whether that's a low-cost stay or a more upscale getaway.
  3. Discover La Mesa using Expedia's trip planning tool: Gain insights into the most popular attractions and best properties for your trip to La Mesa. You can also save your must-visit places, collaborate with family and friends and organize all your plans in one place.
  4. Work out your trip length: Consider how long you'd like to spend exploring La Mesa. Plan your days so you can get to all the activities and attractions you're interested in without rushing.
  5. Bundle your accommodations and airfare: Once you've nailed down your trip dates and duration, book the right La Mesa vacation package for you.
  6. Book activities and experiences ahead of time: Whether it's entrance to a major attraction or a day trip in nature, you won't have to worry about missing out on the best La Mesa has to offer. Find all the incredible things to do in La Mesa with our dedicated activity guide.

Does Expedia offer Book Now, Pay Later La Mesa vacation packages?
If you're like us, you love going away but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the total cost of your La Mesa vacation over 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure great vacation packages with payment plans as soon as you see them.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.