La Mesa Vacations from $350

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Your La Mesa Vacation

Lock in a La Mesa vacation package that includes everything you need and nothing you don't. Good for gift and craft shops, dining and nightlife, think about staying in the neighborhood of Downtown San Diego. The Magnolia, Santee Lakes and Grossmont College are just a few of the attractions you'll want to explore during your trip to La Mesa. Browse Expedia's wide range of travel options and start organizing your perfect vacation to La Mesa today.

The Latest La Mesa vacation packages

Price found within the past 48 hours. Click for updated prices.
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Save 100% on your flight
Price was $580, price is now $350 per person
$350
per person
Feb 14 - Feb 16
found 1 day ago
Roundtrip flight included
Chicago (CHI) to San Diego (SAN)
8.4/10 Very Good! (1,627 reviews)
There is no restaurant in the hotel and also no Iron in the room…

Reviewed on Dec 8, 2025

Quiet Mind Mountain Lodge, Retreat and Spa

Quiet Mind Mountain Lodge, Retreat and Spa

4.5 out of 5
Save 100% on your flight
Price was $633, price is now $355 per person
$355
per person
Jan 22 - Jan 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
9.2/10 Wonderful! (558 reviews)
Great views, and quite with peace.

Reviewed on Dec 8, 2025

Hyatt Vacation Club at The Welk, San Diego Area

Hyatt Vacation Club at The Welk, San Diego Area

3.5 out of 5
Lawrence Welk Resort Village
Save 100% on your flight
Price was $927, price is now $524 per person
$524
per person
Feb 12 - Feb 19
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.2/10 Very Good! (1,508 reviews)
the property is very clean and safe. the cleaning upstairs i wish was quieter though. very good hotel

Reviewed on Dec 9, 2025

Los Bungalows

Los Bungalows

2.5 out of 5
Save 100% on your flight
Price was $1,143, price is now $697 per person
$697
per person
Jan 15 - Jan 21
found 1 day ago
Roundtrip flight included
Chicago (CHI) to San Diego (SAN)
8.2/10 Very Good! (498 reviews)
I know some reviews says it doesn’t have heat or ac but it does. It also said it doesn’t have free parking but it does- 1 car per room. The host was great on communication throughout my stay and before. It was in a great neighborhood and right across from the beach! I would definitely recommend staying here and I will be coming back!

Reviewed on Dec 1, 2025

Urban Boutique Hotel

Urban Boutique Hotel

3 out of 5
Downtown San Diego
Save 100% on your flight
Price was $728, price is now $447 per person
$447
per person
Feb 22 - Feb 28
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.6/10 Excellent! (1,273 reviews)
The staff was very friendly, room CLEAN. everything that I wanted to go too in little Italy was walking distance

Reviewed on Dec 7, 2025

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Discover the most popular places to visit in La Mesa

Mount Helix Park

5/5(1 review)

Learn about the local history of Casa de Oro-Mount Helix when you spend time at Mount Helix Park. Amble around this family-friendly area's waterfront or attend a sporting event.

Mount Helix Park

Computer Museum of America

You can spend an afternoon studying the exhibits at Computer Museum of America during your trip to La Mesa. Attend a sporting event while in this walkable area or simply enjoy the top-notch restaurants.

Computer Museum of America

What to do in La Mesa

San Diego Old Town Trolley Hop-On Hop-Off Tour

San Diego Old Town Trolley Hop-On Hop-Off Tour

$55
per adult
94% of travellers recommend
San Diego Old Town Trolley Hop-On Hop-Off Tour
San Diego: Luggage Storage in Marina

San Diego: Luggage Storage in Marina

$8
per adult
San Diego: Luggage Storage in Marina
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway

San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway

$124
per adult
86% of travellers recommend
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway
See all activities in La Mesa

La Mesa Hotel Deals

Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $154 total per night from Jan 5 to Jan 6
$154 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
9/10 Wonderful! (3,159 reviews)
Hot tub! Room #253 is perfect.

Reviewed on Dec 4, 2025

Bay Club Hotel & Marina
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $175 total per night from Dec 14 to Dec 15
$175 total
Dec 14 - Dec 15
Total with taxes and fees
9/10 Wonderful! (2,954 reviews)
Everything was super comfortable and the room was surprisingly affordable for the amenities you get. We will definitely stay there again if we go to San Diego.

Reviewed on Dec 7, 2025

Legacy Resort Hotel & Spa
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $120 total per night from Dec 16 to Dec 17
$120 total
Dec 16 - Dec 17
Total with taxes and fees
8.8/10 Excellent! (718 reviews)
Great little boutique hotel ! Friendly staff as well

Reviewed on Dec 7, 2025

The DEXTRO Little Italy, BW Premier Collection
See all 8,328 properties in La Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best La Mesa Vacation Packages

La Mesa Essential Information

Language
English
Currency
U.S dollars
Closest Airport
San Diego Intl. Airport (SAN)
Population
60,100
Max Temp Winter
65ºF
Max Temp Summer
80ºF
Top Sights
San Diego Zoo, Coronado Beach and Old Town San Diego State Park

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Frequently asked questions

How much does a La Mesa vacation package cost?
Offering great value package deals from $350 on Expedia, you'll be pleasantly surprised at how much a vacation to La Mesa costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to La Mesa?
January, October and December are the best times to search for cheap La Mesa vacation packages. Opting to travel in quieter months means you can typically find lower prices on flights and hotels.
How many days is enough for La Mesa?
Usually, a handful of days is enough to visit the major attractions during your La Mesa vacation. However, if you prefer to have some time to chill out or go on day trips, think about extending your trip.
Is it worth booking a vacation package to La Mesa?
It's no wonder a La Mesa vacation is on the to-do list of many travelers. Well-known attractions like Mount Helix Park are just the beginning of things to keep you busy here.
How to find the best La Mesa package deals?
Use Expedia's filters to help you find some fabulous La Mesa package deals. When you start your search, just set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your adventure for midweek, or look for La Mesa package deals in the low season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's usually best to book your vacation package well in advance.
Is it cheaper to book a La Mesa vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your flight, hotel and car rental into one great-value price and enjoy significant savings. You'll usually score a better deal than booking each component individually. And you'll still get the freedom to create a personalized La Mesa vacation by choosing your favorite type of stay, airline and car class.
When to book a vacation package to La Mesa?
Secure fantastic discounts by reserving your flights in advance with Expedia. If being spontaneous is more your style, take advantage of our last-minute deals for an impromptu La Mesa adventure.
How to plan a trip to La Mesa?

  1. Pick your travel dates: What you plan to do in La Mesa and your favorite season will help you decide when to get away.
  2. Set your budget: Factor in expenses like food, flights and transportation when calculating how much to set aside for your trip to La Mesa. Then, choose a property that matches your budget, whether that's a low-cost stay or a more upscale getaway.
  3. Discover La Mesa using Expedia's trip planning tool: Gain insights into the most popular attractions and best properties for your trip to La Mesa. You can also save your must-visit places, collaborate with family and friends and organize all your plans in one place.
  4. Work out your trip length: Consider how long you'd like to spend exploring La Mesa. Plan your days so you can get to all the activities and attractions you're interested in without rushing.
  5. Bundle your accommodations and airfare: Once you've nailed down your trip dates and duration, book the right La Mesa vacation package for you.
  6. Book activities and experiences ahead of time: Whether it's entrance to a major attraction or a day trip in nature, you won't have to worry about missing out on the best La Mesa has to offer. Find all the incredible things to do in La Mesa with our dedicated activity guide.

Does Expedia offer Book Now, Pay Later La Mesa vacation packages?
If you're like us, you love going away but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the total cost of your La Mesa vacation over 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure great vacation packages with payment plans as soon as you see them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.